منابع مشابه
Glucose Variability
The proposed contribution of glucose variability to the development of the complications of diabetes beyond that of glycemic exposure is supported by reports that oxidative stress, the putative mediator of such complications, is greater for intermittent as opposed to sustained hyperglycemia. Variability of glycemia in ambulatory conditions defined as the deviation from steady state is a phenome...
متن کاملCharacterizing blood glucose variability using new metrics with continuous glucose monitoring data.
OBJECTIVE Glycemic variability contributes to oxidative stress, which has been linked to the pathogenesis of the long-term complications of diabetes. Currently, the best metric for assessing glycemic variability is mean amplitude of glycemic excursion (MAGE); however, MAGE is not in routine clinical use. A glycemic variability metric in routine clinical use could potentially be an important mea...
متن کاملGlucose variability and complications.
In this issue of the Diabetes Care, Kilpatrick et al. (1) report their analysis of the large Diabetes Control and Complications Trial (DCCT) database on the relationship between glucose variability and relative risk of developing microangiopathic complications in type 1 diabetes. They find that glucose variability (intraday blood glucose excursions) does not play a role and conclude that only e...
متن کاملReduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: interest of continuous glucose monitoring.
OBJECTIVE To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS The CGMS enabled recording of subcutaneous glucose concentrations (range 2.2-22 mmol/l) over 72 h (288 measurements per ...
متن کاملEditorial Blood Pressure Variability
Copyright © 2010 American Heart Association. All rights reserved. Print ISSN: 0194-911X. Online 72514 Hypertension is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/HYPERTENSIONAHA.110.154708 published online Jul 6, 2010; Hypertension Eamon Dolan and Eoin O'Brien Blood Pressure Variability. Clarity for Clinical Practice http://hyper.ahajournals.org ...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2015
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2015.01.021